Stimulant — methylphenidate

Ritalin

Also marketed as: Methylin

Methylphenidate (immediate release)

DEA Schedule II FDA approved adults Pediatric ages 6+

How it works

Blocks reuptake of dopamine and norepinephrine via DAT and NET inhibition.

At-a-glance

Onset of effect
0.25–0.5 h
Typical duration of effect
3–4 h
Half-life
~2–3 (parent), ~3–6 (active metabolite)
Formulations
Oral tablet (IR), Chewable, Liquid
Adult dose range
5–60 mg/day, split into 2–3 doses
FDA max: 60 mg/day
Pediatric dose range
5–60 mg/day depending on age

Common side effects

  • Decreased appetite
  • Insomnia
  • Headache
  • Stomach ache

Important warnings

  • Schedule II
  • Cardiovascular risk

Source

Reference data is sourced from the current FDA prescribing information at DailyMed. Dose ranges, approved ages, and warnings change over time — always check the current label and consult your prescriber.

FDA prescribing information at DailyMed →

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