Stimulant — methylphenidate
Focalin XR
Dexmethylphenidate (extended release)
DEA Schedule II FDA approved adults
Pediatric ages 6+
How it works
Pure d-isomer of methylphenidate (the more pharmacologically active enantiomer). Same DAT/NET reuptake inhibition.
At-a-glance
- Onset of effect
- 0.5–1.5 h
- Typical duration of effect
- 10–12 h
- Half-life
- ~2–4 (bimodal release)
- Formulations
- Oral capsule (XR, beaded)
- Adult dose range
- 10–40 mg once daily
FDA max: 40 mg/day (adults), 30 mg/day (children) - Pediatric dose range
- 5–30 mg once daily
Common side effects
- Decreased appetite
- Insomnia
- Dry mouth
- Anxiety
Important warnings
- Schedule II
- Cardiovascular risk
Notes
Roughly half the mg dose of racemic methylphenidate gives equivalent effect.
Source
Reference data is sourced from the current FDA prescribing information at DailyMed. Dose ranges, approved ages, and warnings change over time — always check the current label and consult your prescriber.